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Free Whitepaper:

Gene Expression: Nuclear Receptors

Xenobiotic receptors regulate gene expression, which makes them potent regulators of the cell cycle and apoptosis, as well as cytochrome p450 enzymes. Responsible for the metabolism of drugs and nutrients, enzyme induction is an important aspect of drug-drug interactions and toxicity. In this free whitepaper, learn more about gene expression through a detailed examination of nuclear receptors.

Download this informative resource today to learn more about nuclear hormone receptors and gene expression to support your own research. 

Download this whitepaper today

This Whitepaper Will Discuss:

  • The main nuclear receptor functional domains and structure
  • The mechanism of gene regulation by nuclear receptors
  • The basics of transcriptional proteins and aryl hydrocarbon receptors
  • The four classifications or types of gene expression activity

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Why Choose Us?

Get what you need from the world's largest portfolio of nuclear receptors

INDIGO has the largest portfolio of cell-based nuclear receptor assays in the world, helping you identify compounds with the highest selectivity and the lowest potential for unwanted effects and off-target responses. Our broad portfolio of nuclear receptors makes us the preferred source for single receptor or full-panel screenings. Whether for nuclear receptor or in vitro toxicology solutions, our intellectual property, ease of use, and quick turnarounds will get you to the next phase of discovery, faster.

Make confident decisions with clear results about your compounds

To empower confident decision-making throughout the discovery process, INDIGO’s technology generates clear single receptor or full-panel screening results, making for better interpretation and more accurate data. Employing a luminescence-based method and our proprietary CryoMite™ preservation process, we provide reproducible results lot to lot about the efficacy, potency, and selectivity of your compounds, plus comprehensive lab reports that include helpful graphics, summaries, and insights.

Be supported in your study with a committed team of experts

INDIGO is a leading provider of nuclear receptor and in vitro toxicology solutions, recognized for our focus on client support. Committed to accelerating the discovery process for you, our team goes the extra mile by offering complimentary study consults, designs, and research, and providing a comprehensive review of the results with you. As objective experts focused on your success, it’s our duty to ensure the results we provide inform assured next steps.

Save time and money with accelerated lab results and decisions

At INDIGO, our cell-based assay kits and services accelerate scientific decision-making by reducing time, cost, and risk associated with the discovery process. We know that time is money during discovery and aim to get you to the next phase faster or prevent unnecessary steps forward. For quick data and decisions, our kits deliver results in just 24 hours. And, beyond saving time, our kits and services also provide the most comprehensive data for your investment.

Screen your compounds using reliable science, platforms, and people

INDIGO provides a superior combination of expertise, kits, services, and support to leading through startup organizations, ranging from pharmaceutical companies and biotechs to university labs and CROs. Lab directors across the globe trust us for single receptor or full-panel screenings at every stage of discovery, leveraging our industry-leading platforms, knowledgeable people, and proprietary science.

About Us

INDIGO Biosciences, Inc. is a leading provider of nuclear receptor and in vitro toxicology solutions that accelerate scientific decision-making. We supplement the world’s largest portfolio of nuclear receptor kits and services and in vitro toxicology solutions with greater results readability, reproducibility, accuracy, and turnaround times. Our solutions, plus supportive team and reliable science and platforms, aim to reduce the time, cost, and risk associated with the discovery process.