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Are Traditional Water Quality Testing Methods Sufficient?

Traditional techniques rely on analyses of individual contaminants. However, real world exposure generally occurs as mixtures of different chemical compounds.

This presents risks to humans and the environment from:

  • chemicals without toxicity information
  • the presence and concentrations of other compounds
  • chemicals that work together to increase toxic potential

To understand the risk posed by complex samples, cell-based assays are needed to characterize cumulative effects of multiple contaminants on humans and other organisms.

INDIGO's Functional Assays: The Next Wave in Evaluating Water Quality

Cell-based reporter assays, such as those provided by INDIGO Biosciences, screen for total bioactivity for a specific pathway of importance. They can detect the toxicity of unknown chemical pollutants and can account for their cumulative effects, simplifying the issues posed by complex mixtures in traditional analytical methods. INDIGO offers a family of in vitro bioassays that are optimized for environmental applications. These include:

  • Aryl Hydrocarbon Receptor (AhR)
  • Androgen Receptor (AR)
  • Estrogen Receptor (ER)
  • Glucocorticoid Receptor (GR)
  • Mineralocorticoid Receptor (MR)

These assays can be used to inform pilot project design, process optimization, and routine water quality monitoring.

Learn More at the 2024 WateReuse Symposium!

Schedule a meeting to discuss cell-based assays and their use in recycled water applications.

INDIGO Biosciences

INDIGO Biosciences, Inc. is a leading provider of cell-based luciferase reporter assays. INDIGO offers assays as all-inclusive kits for use by scientists in their own labs, or INDIGO can perform the assays as a service. INDIGO products and services are used in a broad range of industries such as environmental toxicology, drug discovery, academia, and contract research organizations. Their assays have been used in labs worldwide and are demonstrated to provide fast, accurate, and reproducible results. INDIGO has a highly qualified technical team of scientists that are dedicated to supporting research clients through reliable, easy-to-use products and custom assay services. Learn more on their website INDIGOBiosciences.com!